KARYA TULIS ILMIAH STUDI PENGGUNAAN OBAT ANTIHIPERTENSI (BISOPROLOL) PADA PASIEN GAGAL JANTUNG RAWAT JALAN DI RUMAH SAKIT “X” PERIODE OKTOBER-DESEMBER 2020


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Abstraksi STUDY OF ANTIHYPERTENSION DRUG (BISOPROLOL)
HEART FAILURE PATIENTS HOSPITAL "X" OUTPATIENT
PERIOD OCTOBER-DECEMBER 2020
Tantrie Yunita
Pharmacy Academy Mitra Sehat Mandiri Sidoarjo
Ki Hajar Dewantara street No.200 Krian-Sidoarjo
E-mail : tantrieyunita0706@gmail.com
Abstract:
Hypertension is a condition in which a person's blood pressure is 140 mmHg or more (systolic
pressure) and 90 mmHg or more (diastolic pressure). Narrowing and blockage of blood vessels
caused by hypertension can increase the risk of heart failure. Bisoprolol is safer and more
effective for controlling heart rate. This research method is descriptive observational with
purposive sampling technique. The number of samples was 40 patients who met the inclusion
criteria with parameters: patient characteristics (gender, age), therapeutic dose, rules of use,
duration of administration, type of therapy (single/combination therapy, single/combination
antihypertensive drug therapy), clinical data (blood pressure) systolic and diastolic). The results
of the research on gender characteristics were mostly male, 65% (n=26) and the most age group in
the late elderly category, 56-65 years, 35% (n=14). The highest dose of bisoprolol tablet was
administered at a therapeutic dose of 5 mg 52.5% (n=21). The most commonly used rule is once a
day 90% (n=36) with the overall duration of therapy given for 30 days 100% (n=100). The most
type of therapy used combination bisoprolol therapy 97.5% (n=39) with the most combinations
being Bisoprolol, Furosemide and Spironolactone as much as 12.5% (n=5). Clinical data (systolic
and diastolic blood pressure) showed the most improvement in blood pressure. systolic blood
pressure decreased 67.5% (n=27) and the highest diastolic blood pressure remained 57.5%
(n=23). Based on the explanation above, it is suggested that further research can use other classes
of antihypertensive as a comparison of its effectiveness and for further clinical data (systolic and
diastolic blood pressure) it can be carried out in less than 1 month so that monitoring of
improvement in patient blood pressure can be observed more significantly.
Keyword: antihypertensives, heart failure, bisoprolol
Pengarang Tantrie Yunita - Personal Name (Pengarang)
Universitas Akademi Farmasi Mitra Sehat Mandiri Sidoarjo
Tahun 2021
Tempat Krian



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