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Afifatut Diana Pengarang Apt. Fahmi Ardianti Purnawiranita, S.Farm., M.Farm Dosen Pembimbing 1 Apt. Fahmi Ardianti Purnawiranita, S.Farm., M.Farm Penguji 2 Apt. Ismu Dwi Supangkat, S.Farm Ketua Penguji Apt. Valiandri Puspadina, S.Farm., M.Farm Penguji 1

ABSTRAK Menstruasi terjadi karena kontraksi otot uterus dan hormone progesterone menurun, sedangkan hormone estrogen meningkat, yang menyebabkan kontraksi otot uterus berlebihan sehingga terjadi dismenore. Beberapa jenis obat yang digunakan remaja putri untuk mengatasi nyeri saat menstruasi berupa terapi farmakologis seperti asam mefenamat dan terapi non-farmakologis seperti kompres hangat. Penelitian ini menggunakan metode survey deskriptif, yaitu suatu penelitian yang digunakan untuk mendeskripsikan atau menggambarkan suatu fenomena yang terjadi dalam masyarakat. Penelitian ini dilakukan dengan cara memberikan kuisioner kepada responden yang sebelumnya sudah di uji validitas dan uji reliabilitas terlebih dahulu dengan bantuan software SPSS. Hasil penelitian ini menunjukkan bahwa pengetahuan siswi tentang penggunaan asam mefenemat untuk meredakan nyeri dismenore yaitu, 97,8% responden berpengetahuan baik, dan 2,2% berpengetahuan cukup baik, sedangkan pengetahuan tentang penggunaan kompres hangat untuk meredakan nyeri dismenore yaitu, 93,3% responden berpengetahuan baik, dan 6,7% responden berpengetahuan cukup baik. ABSTRACT Menstruation occurs because uterine muscle contractions and the hormone progesterone decreases, while the hormone estrogen increases, which causes excessive uterine muscle contractions resulting in dysmenorrhea. Some types of drugs used by adolescent girls to treat pain during menstruation are pharmacological therapies such as mefenamic acid and non-pharmacological therapies such as warm compresses. This research uses a descriptive survey method, which is a study used to describe or describe a phenomenon that occurs in society. This research was conducted by giving questionnaires to respondents who had previously been tested for validity and reliability testing first with the help of SPSS software. The results of this study showed that the knowledge of female students about the use of mefenemic acid to relieve dysmenorrhea pain, that is, 97.8% of respondents were well knowledgeable, and 2.2% were quite well knowledge, while knowledge about the use of warm compresses to relieve dysmenorrhea pain was, 93.3% of respondents were well knowledgeable, and 6.7% of respondents were quite well knowledged.